Sabin Vaccine Institute – Blavatnik Family Foundation

New Marburg Outbreaks in Africa Raise Alarm About the Deadly Virus’s Spread

Posted on April 3, 2023 (April 4, 2023) by Christine Ongsueng

World Health Organization officials visited the home of a possible victim of the Marburg virus during an outbreak in Angola in 2005. There are currently two outbreaks on both the west and east coasts of Africa. Credit: Mike Hutchings/Reuters

Dr. Sullivan designed the Marburg vaccine candidate farthest along in development when she worked with the National Institute of Allergy and Infectious Diseases. It showed safety and immune response in a Phase 1 clinical trial, and the Sabin Vaccine Institute, a nonprofit organization based in Washington that promotes global vaccine development, is continuing the testing process. The Sabin Institute said it had 600 doses of the vaccines in vials and ready to use and planned for an eventual stockpile of 8,000 by the end of this year. […]

‘Ebola Could Have Wiped Us All’: Slow Lockdown Haunts Uganda

Posted on December 8, 2022 (January 17, 2023) by Christine Ongsueng

Vaccines exist to prevent Ebola, but there is no approved vaccine or drug treatment for the Sudan strain of the virus, which caused the recent outbreak in Uganda. A clinical trial of three vaccines — made by the Washington-based Sabin Vaccine Institute, the University of Oxford and the American pharmaceutical company Merck — is being prepared. Researchers have also begun a clinical trial of two monoclonal antibodies donated by the United States that can help boost patients’ chances of survival. […]

Sabin Vaccine Institute Delivers Ebola Sudan Vaccine to Fight Outbreak in Uganda

Posted on December 8, 2022 (January 17, 2023) by Christine Ongsueng

Sabin Vaccine Institute is the first organization to provide the World Health Organization (WHO) its Ebola Sudan vaccine to help with the Ebola Sudan outbreak in Uganda. Approximately 1,100 doses of Sabin’s vaccine are now in Uganda. Another 8,500 doses will be made available to WHO on a rolling basis through January. The WHO announced last month that Sabin’s Ebola Sudan vaccine would be one of three vaccines included in a planned ring vaccination trial in Uganda, following the recommendation of a WHO-convened independent expert committee. Sabin also plans to supply a further 25,000 doses early next year. There is no approved vaccine for Ebola Sudan yet; the outbreak, which is now waning, began in Uganda in September and to date has killed at least 55 people. […]